Mission Statement

Our lab focuses on identifying therapeutic targets to preserve skeletal and cardiac muscle function within the context of disuse (e.g., immobilization and hospitalization), sarcopenia, diabetes, and heart failure. Intracellular and cross-tissue pathways responsible for the beneficial effects of exercise are also of major interest. We conduct pre-clinical studies primarily combining unbiased approaches (e.g., proteomics, metabolomics) with molecular biology and mouse genetics.